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Estradiol (E2)

Estradiol (E2)

Pre test Information : No Special Preparation Needed


An oestrogen test determines the concentration of estrogens in the blood or urine. Estrogen levels in saliva can also be measured using an at-home test kit. Estrogens are a class of hormones that play an important role in the development of female physical characteristics and reproductive functions, such as breast and uterine growth and menstrual cycle regulation. Men produce oestrogen as well, but in much smaller quantities.

There are many different types of estrogens, but only three are commonly tested for:

  • Estrone, also known as E1, is the primary female hormone produced by women after menopause. Menopause is the period in a woman's life when her menstrual periods cease and she is no longer able to become pregnant. It usually begins around the age of 50. 
  • It usually begins around the age of 50. 
  • Estriol, also known as E3, is a hormone that rises during pregnancy.

Measuring oestrogen levels can provide important information about your fertility (ability to conceive), pregnancy health, menstrual cycle, and other health conditions.

Estradiol test, estrone (E1) test, estradiol (E2) test, estriol (E3) test, estrogenic hormone test

What is its purpose?

Estradiol tests, also known as estrone tests, are used to:

  • Determine the cause of early or late puberty in girls 
  • Determine the cause of late puberty in boys 
  • Determine the cause of early or late puberty in girls • Determine the cause of late puberty in boys • Diagnose menstrual problems 
  •  Determine the cause of infertility (the inability to become pregnant)
  • Monitor infertility treatments 
  • Monitor menopause treatments
  • Assist in the diagnosis of certain birth defects during pregnancy using an estriol hormone test.
  • Track a high-risk pregnancy

What is the purpose of an oestrogen test?

  • Are having difficulty getting pregnant
  • Are a woman of childbearing age who is not having periods or has abnormal periods 
  • Are a girl with early or delayed puberty 
  • Have symptoms of menopause, such as hot flashes and/or night sweats 
  • Have vaginal bleeding after menopause 
  • Are a boy with delayed puberty 
  • Are having difficulty getting pregnant 
  • Are a woman of childbearing age who is not having periods or has abnormal periods 
  • Are a girl with early or delayed puberty 
  • Have symptoms of menopause, such as hot flashes and/or night sweats 
  • Have vaginal bleeding after menopause 
  • Are a boy with delayed puberty 
  • Are a man showing female characteristics, such as breast growth

If you are pregnant, your doctor may order an estriol test between the 15th and 20th week of your pregnancy as part of a triple screen test. It can determine whether your baby is at risk for a genetic birth defect like Down syndrome. An estriol test is not required for all pregnant women, but it is recommended for those who are at a higher risk of having a baby with a birth defect. If you have a family history of birth defects, are 35 or older, have diabetes, or have had a viral infection during pregnancy, you may be at a higher risk.



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